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  • 產(chǎn)品名稱：CCDC112 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：

中文名稱：CCDC112 抗原（重組蛋白）

英文名稱：CCDC112 Antigen (Recombinant Protein)

別    名：  coiled-coil domain containing 112; MBC1

儲    存：  冷凍（-20℃） 

相關(guān)類別：抗原

概     述

Fusion protein corresponding to a region derived from 247-446 amino acids of human CCDC112

技術(shù)規(guī)格

Full name:

coiled-coil domain containing 112

Synonyms:

MBC1

Swissprot:

Q8NEF3

Gene Accession:

BC031242

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

CCDC112 (coiled-coil domain containing 112), also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.





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