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  • 產(chǎn)品名稱：C4BPB 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
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詳情介紹：

中文名稱： C4BPB 抗原（重組蛋白）


英文名稱： C4BPB Antigen (Recombinant Protein)

別     名：  complement component 4 binding protein beta; C4BP

儲(chǔ)     存：  冷凍（-20℃）  

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 21-251 amino acids of human C4BPB


技術(shù)規(guī)格

Full name:

complement component 4 binding protein beta

Synonyms:

C4BP

Swissprot:

P20851

Gene Accession:

BC005378

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.



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