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  • 產(chǎn)品名稱：兔抗MDM2(PhosphoSer186/Ser188) 多克隆抗體

  • 產(chǎn)品型號：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1800
  • 產(chǎn)品庫存：60
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兔抗MDM2(Phospho-Ser186/Ser188) 多克隆抗體公司是一家集科研、開發(fā)、銷售為一體的高科技企業(yè)，主要經(jīng)營進(jìn)出口化學(xué)試劑，ELISA試劑盒、生命科學(xué)科研產(chǎn)品、實(shí)驗(yàn)室設(shè)備、耗材等，為了更好的服務(wù)好每一位顧客，始終把產(chǎn)品品質(zhì)和人力資源視為企業(yè)發(fā)展的原動(dòng)力。
詳情介紹：


中文名稱：  兔抗MDM2(Phospho-Ser186/Ser188) 多克隆抗體 

英文名稱： Anti-MDM2(Phospho-Ser186/Ser188) rabbit polyclonal antibody

別      名： HDMX; hdm2; ACTFS

相關(guān)類別： 一抗

儲(chǔ)      存： 冷凍（-20℃） 避光

宿      主： Rabbit

抗      原： MDM2(Phospho-Ser186/Ser188)

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類型： Unconjugate 

技術(shù)規(guī)格

Background:

This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues.

Applications:

IF

Name of antibody:

MDM2(Phospho-Ser186/Ser188)

Immunogen:

Peptide sequence around phosphorylation site of Ser186/Ser188(H-K-S(p)-D-S(p)-I-S) derived from Human MDM2.

Full name:

MDM2 proto-oncogene, E3 ubiquitin protein ligase

Synonyms：

HDMX; hdm2; ACTFS

SwissProt:

Q00987

IF positive control:

Hela cells

IF Recommend dilution:

100-200


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