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  • 產(chǎn)品名稱:PLGLB2 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
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詳情介紹:


中文名稱: PLGLB2 抗原(重組蛋白)

英文名稱: PLGLB2 Antigen (Recombinant Protein)

別     名:  plasminogen-like B2; PLGP1

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 20-96 amino acids of human PLGLB2

技術(shù)規(guī)格

Full name:

plasminogen-like B2

Synonyms:

PLGP1

Swissprot:

Q02325

Gene Accession:

BC005379

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. PLGLB2 (plasminogen-like B2), also known as PLGP1, is a 96 amino acid protein that resembles the N-terminal plasminogen activation peptide, which is released from plasminogen during conversion to plasmin. PLGLB2 may bind to lysine binding sites present in the kringle structures of plasminogen, an event that interfers with the binding of fibrin or α-2 antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.





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